Index

Tubular carcinoma

Sclerosing adenosis

Microglandular adenosis

Radial scar

Infiltrative, often stellate architecture

Lobulocentric architecture

Infiltrative, disorderly architecture

Complex, stellate architecture

Desmoplastic stroma
Central elastosis frequent

Often central cellularity
with sclerotic periphery

Fibrotic stroma

Variable stromal cellularity

Well formed, angulated tubules

Distorted, compressed tubules
Frequent obliterated lumina

Uniform, round tubules

Distorted tubules

Abundant eosinophilic cytoplasm, often with apical snouts

Infrequent apical snouts

Clear, vacuolated or granular epithelial cytoplasm.
No apical snouts

No apical snouts

Absent myoepithelial cells

Prominent admixed myoepithelial cells

Occasional myoepithelial cells described

Myoepithelial cells seen

Patchy, incomplete basement membrane

Uniform basement membrane

Prominent basement membrane

Basement membrane seen

Intraluminal secretion or microcalcification may be seen

Intraluminal microcalcification may be seen

Intraluminal colloid-like material which may be calcified

Intraluminal secretion uncommon.
Microcalcification may be seen

Frequent associated low grade cribriform or micropapillary DCIS

May be associated apocrine metaplasia.
Associated DCIS or lobular neoplasia are rare but described

Atypical features rarely described (see text)

Associated cysts, sclerosing adenosis, epithelial hyperplasia and rarely in situ or invasive carcinoma

Index