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TABLE 4

BM BIOPSY: LYMPHOID NODULES
MALIGNANCY VERSUS REACTIVE PROCESS

		Nodules in FCL*		Reactive nodules
Size		usually large		usually small
Number		multiple		unique or multiple
Localization		paratrabecular		intertrabecular
Borders		not sharp		sharp
Germinal centers		usually absent		possible, unusual
IHC		usually B > T		usually B < T
FDC**		often present		unusual

*FCL = Follicular Center Lymphoma
**FDC = Follicular Dendritic Cell.

No absolute criteria !

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Copyright 2001, The Author(s) and/or The Publisher(s)

Organisation: FORPATH asbl

Coordination: Dr Bernard Van den Heule

Host: Labo CMP